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Lupus Nephritis Summary

Description: Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982).

Also Known As: Glomerulonephritides, Lupus; Lupus Glomerulonephritides; Lupus Nephritides; Nephritides, Lupus; Glomerulonephritis, Lupus Show All >>

Networked: 3205 relevant articles (321 outcomes, 494 trials/studies) for this Disease

Key Drugs and Agents for Lupus Nephritis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cyclophosphamide (Cytoxan) : 82 outcomes 93 studies in 424 results : FDA 10 Generic
  2. mycophenolate mofetil (Cellcept) : 45 outcomes 59 studies in 213 results : FDA 24 Generic
  3. rituximab (Mabthera) : 24 outcomes 22 studies in 75 results : FDA 3
  4. Tacrolimus (Prograf) : 19 outcomes 17 studies in 58 results : FDA 7 Generic
  5. Azathioprine (Imuran) : 18 outcomes 31 studies in 105 results : FDA 7 Generic
  6. Steroids : 17 outcomes 7 studies in 60 results : IBA
  7. Adrenal Cortex Hormones (Corticosteroids) : 16 outcomes 11 studies in 90 results : IBA
  8. Methylprednisolone : 14 outcomes 9 studies in 73 results : FDA 18 Generic
  9. Prednisone (Sone) : 13 outcomes 15 studies in 62 results : FDA 119 Generic
  10. Cyclosporine (Ciclosporin) : 11 outcomes 13 studies in 55 results : FDA 20 Generic
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Diseases Related to Lupus Nephritis

  1. Systemic Lupus Erythematosus (Libman-Sacks Disease)
  2. Proteinuria
  3. Vasculitis (Vasculitides)
  4. Glomerulonephritis
  5. Nephrotic Syndrome (Syndrome, Nephrotic)
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Key Therapies for Lupus Nephritis

Efficacy Chart >>
  1. Plasma Exchange : 4 outcomes 3 studies in 17 results
  2. Plasmapheresis : 3 outcomes 16 studies in 45 results
  3. Transplants (Transplant) : 3 outcomes 10 studies in 72 results
  4. Kidney Transplantation : 3 outcomes 9 studies in 57 results
  5. Remission Induction : 3 outcomes 4 studies in 16 results
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