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Systemic Lupus Erythematosus (Libman-Sacks Disease) Summary

Description: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Also Known As: Libman-Sacks Disease; Lupus Erythematosus, Systemic; Disease, Libman-Sacks; Libman Sacks Disease; Lupus Erythematosus Disseminatus

Networked: 16725 relevant articles (479 outcomes, 1518 trials/studies) for this Disease

Key Drugs and Agents for Systemic Lupus Erythematosus

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cyclophosphamide (Cytoxan) : 34 outcomes 33 studies in 308 results : FDA 10 Generic
  2. rituximab (Mabthera) : 33 outcomes 36 studies in 223 results : FDA 3
  3. Antigen-Antibody Complex (Immune Complex) : 25 outcomes 25 studies in 609 results : IBA
  4. DNA (Deoxyribonucleic Acid) : 17 outcomes 82 studies in 1326 results : IBA
  5. Antibodies : 16 outcomes 158 studies in 2409 results : IBA
  6. Adrenal Cortex Hormones (Corticosteroids) : 16 outcomes 20 studies in 218 results : IBA
  7. Prednisone (Sone) : 16 outcomes 11 studies in 131 results : FDA 119 Generic
  8. Immunoglobulin G (IgG) : 15 outcomes 55 studies in 749 results : IBA
  9. Autoantibodies : 14 outcomes 93 studies in 1739 results : IBA
  10. mycophenolate mofetil (Cellcept) : 14 outcomes 11 studies in 100 results : FDA 24 Generic
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Diseases Related to Systemic Lupus Erythematosus

  1. Autoimmune Diseases (Autoimmune Disease)
  2. Rheumatoid Arthritis
  3. Lupus Nephritis
  4. Vasculitis (Vasculitides)
  5. Glomerulonephritis
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Key Therapies for Systemic Lupus Erythematosus

Efficacy Chart >>
  1. Transplantation (Transplant Recipients) : 8 outcomes 13 studies in 79 results
  2. Plasmapheresis : 8 outcomes 8 studies in 97 results
  3. Plasma Exchange : 7 outcomes 3 studies in 70 results
  4. Transplants (Transplant) : 6 outcomes 8 studies in 125 results
  5. Hematopoietic Stem Cell Transplantation : 4 outcomes 3 studies in 37 results
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