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Liposarcoma Summary

Description: A malignant tumor derived from primitive or embryonal lipoblastic cells. It may be composed of well-differentiated fat cells or may be dedifferentiated: myxoid (LIPOSARCOMA, MYXOID), round-celled, or pleomorphic, usually in association with a rich network of capillaries. Recurrences are common and dedifferentiated liposarcomas metastasize to the lungs or serosal surfaces. (From Dorland, 27th ed; Stedman, 25th ed)

Also Known As: Dedifferentiated Liposarcoma; Dedifferentiated Liposarcomas; Liposarcomas; Liposarcomas, Dedifferentiated; Liposarcomas, Pleomorphic Show All >>

Networked: 909 relevant articles (32 outcomes, 89 trials/studies) for this Disease

Key Drugs and Agents for Liposarcoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. trabectedin (ecteinascidin 743) : 7 outcomes 10 studies in 34 results : IBA
  2. Ifosfamide : 3 outcomes 4 studies in 14 results : FDA 7 Generic
  3. Doxorubicin (Adriamycin) : 2 outcomes 3 studies in 16 results : FDA 12 Generic
  4. Dermatofibrosarcoma protuberans : 2 outcomes 2 studies in 31 results : IBA
  5. Taxoids : 2 outcomes in 5 results : IBA
  6. zoledronic acid (zoledronate) : 2 outcomes in 2 results : FDA 13
  7. PPAR gamma : 1 outcome 6 studies in 19 results : IBA
  8. MicroRNAs (MicroRNA) : 1 outcome 4 studies in 11 results : IBA
  9. troglitazone (Rezulin) : 1 outcome 3 studies in 5 results : FDA 2
  10. DNA (Deoxyribonucleic Acid) : 1 outcome 2 studies in 30 results : IBA
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Diseases Related to Liposarcoma

  1. Leiomyosarcoma
  2. Neoplasms (Cancer)
  3. Sarcoma (Soft Tissue Sarcoma)
  4. Lipoma (Lipomata)
  5. Hemangiosarcoma (Angiosarcoma)
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Key Therapies for Liposarcoma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 8 outcomes 5 studies in 68 results
  2. Radiotherapy : 2 outcomes 2 studies in 38 results
  3. Adjuvant Chemotherapy : 2 outcomes 1 study in 7 results
  4. Combination Drug Therapy (Combination Chemotherapy) : 2 outcomes in 4 results
  5. Heterologous Transplantation (Xenotransplantation) : 2 studies in 15 results
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