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Ligases Summary

Description: A class of enzymes that catalyze the formation of a bond between two substrate molecules, coupled with the hydrolysis of a pyrophosphate bond in ATP or a similar energy donor. (Dorland, 28th ed) EC 6.

Also Known As: Synthetase; Synthetases

Networked: 2113 relevant articles (46 outcomes, 157 trials/studies) for this Bio-Agent

Key Diseases for which Ligases is Relevant

  1. Neoplasms (Cancer) : 6 outcomes 18 studies in 269 results
  2. Infection : 6 outcomes 5 studies in 138 results
  3. Myositis (Idiopathic Inflammatory Myopathies) : 3 outcomes 6 studies in 71 results
  4. Reperfusion Injury : 3 outcomes 2 studies in 20 results
  5. Muscular Atrophy (Muscle Atrophy) : 2 outcomes 8 studies in 83 results
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Drugs Related to Ligases

  1. Ubiquitin
  2. Poly Adenosine Diphosphate Ribose
  3. gamma-glutamylcysteine
  4. Acyl Coenzyme A (Acyl CoA)
  5. Nitric Oxide (Nitrogen Monoxide)
  6. Carbamyl Phosphate (Carbamoyl Phosphate)
  7. Glutathione (Reduced Glutathione)
  8. ozagrel
  9. Epoprostenol (Prostacyclin)
  10. DNA (Deoxyribonucleic Acid)
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Therapies Related to Ligases

  1. Therapeutics
  2. Drug Therapy (Chemotherapy)
  3. Aftercare (After-Treatment)
  4. Denervation
  5. Transplantation (Transplant Recipients)
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