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Visceral Leishmaniasis (Kala Azar) Summary

Description: A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.

Also Known As: Kala Azar; Leishmaniasis, Visceral; Fever, Black; Black Fever; Kala-Azar

Networked: 2641 relevant articles (286 outcomes, 332 trials/studies) for this Disease

Key Drugs and Agents for Visceral Leishmaniasis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. liposomal amphotericin B : 40 outcomes 17 studies in 153 results : FDA 2
  2. Amphotericin B (Amphotericin) : 39 outcomes 25 studies in 160 results : FDA 12 Generic
  3. miltefosine : 29 outcomes 21 studies in 176 results : IBA
  4. Antigens : 28 outcomes 50 studies in 377 results : IBA
  5. Antimony : 24 outcomes 16 studies in 196 results : IBA
  6. Antimony Sodium Gluconate (Sodium, Stibogluconate) : 19 outcomes 18 studies in 123 results : IBA
  7. Liposomes (Liposome) : 14 outcomes 3 studies in 48 results : IBA
  8. Fluorometholone (FML) : 10 outcomes 4 studies in 25 results : FDA 6
  9. Paromomycin (Paromomycin Sulfate) : 8 outcomes 16 studies in 62 results : FDA 5 Generic
  10. Saponins : 8 outcomes 2 studies in 20 results : IBA
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Diseases Related to Visceral Leishmaniasis

  1. Infection
  2. Visceral Leishmaniasis (Kala Azar)
  3. Leishmaniasis
  4. Cutaneous Leishmaniasis
  5. Acquired Immunodeficiency Syndrome (AIDS)
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Key Therapies for Visceral Leishmaniasis

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 11 outcomes 11 studies in 93 results
  2. Aftercare (After-Treatment) : 5 outcomes 2 studies in 57 results
  3. Immunotherapy : 4 outcomes 3 studies in 28 results
  4. Injections : 2 outcomes 1 study in 11 results
  5. Oral Administration : 2 outcomes in 7 results
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