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Leiomyosarcoma Summary

Description: A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865)

Also Known As: Epithelioid Leiomyosarcoma; Epithelioid Leiomyosarcomas; Leiomyosarcomas; Leiomyosarcomas, Epithelioid; Leiomyosarcomas, Myxoid Show All >>

Networked: 1737 relevant articles (67 outcomes, 148 trials/studies) for this Disease

Key Drugs and Agents for Leiomyosarcoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. gemcitabine : 9 outcomes 13 studies in 52 results : FDA 7
  2. trabectedin (ecteinascidin 743) : 9 outcomes 11 studies in 46 results : IBA
  3. Doxorubicin (Adriamycin) : 9 outcomes 8 studies in 54 results : FDA 12 Generic
  4. docetaxel (Taxotere) : 6 outcomes 10 studies in 37 results : FDA 3
  5. Ifosfamide : 5 outcomes 6 studies in 26 results : FDA 7 Generic
  6. Paclitaxel (Taxol) : 2 outcomes 4 studies in 11 results : FDA 13 Generic
  7. temozolomide (Temodar) : 2 outcomes 3 studies in 8 results : FDA 3 Generic
  8. bevacizumab : 2 outcomes 1 study in 5 results : FDA 2
  9. Taxoids : 2 outcomes in 6 results : IBA
  10. Estrogens (Estrogen) : 1 outcome 7 studies in 34 results : FDA 1
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Diseases Related to Leiomyosarcoma

  1. Neoplasms (Cancer)
  2. Sarcoma (Soft Tissue Sarcoma)
  3. Liposarcoma
  4. Neoplasm Metastasis (Metastasis)
  5. Myxoid Liposarcoma
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Key Therapies for Leiomyosarcoma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 21 outcomes 18 studies in 178 results
  2. Radiotherapy : 5 outcomes 1 study in 74 results
  3. Heterologous Transplantation (Xenotransplantation) : 1 outcome 1 study in 17 results
  4. Combination Drug Therapy (Combination Chemotherapy) : 1 outcome 1 study in 11 results
  5. Adjuvant Chemotherapy : 1 outcome in 17 results
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