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Kuru Summary

Description: A prion disease found exclusively among the Fore linguistic group natives of the highlands of NEW GUINEA. The illness is primarily restricted to adult females and children of both sexes. It is marked by the subacute onset of tremor and ataxia followed by motor weakness and incontinence. Death occurs within 3-6 months of disease onset. The condition is associated with ritual cannibalism, and has become rare since this practice has been discontinued. Pathologic features include a noninflammatory loss of neurons that is most prominent in the cerebellum, glial proliferation, and amyloid plaques. (From Adams et al., Principles of Neurology, 6th ed, p773)

Also Known As: Encephalopathy, Kuru; Kuru Encephalopathy

Networked: 133 relevant articles (1 outcomes, 7 trials/studies) for this Disease

Key Drugs and Agents for Kuru

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Amyloid (Amyloid Fibrils) : 1 outcome 2 studies in 31 results : IBA
  2. Acquired CJD : 1 outcome 1 study in 18 results : IBA
  3. Antibodies : 3 studies in 10 results : IBA
  4. Methionine (L-Methionine) : 2 studies in 7 results : FDA 30
  5. Codon (Codons) : 1 study in 17 results : IBA
  6. Valine (L-Valine) : 1 study in 6 results : FDA 31
  7. Paraffin : 1 study in 5 results : IBA
  8. Peptides : 1 study in 2 results : IBA
  9. Ferritins (Ferritin) : 1 study in 1 result : IBA
  10. dicyanmethane (malononitrile) : 1 study in 1 result : IBA
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Diseases Related to Kuru

  1. Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
  2. Scrapie
  3. Bovine Spongiform Encephalopathy (Mad Cow Disease)
  4. Amyloid Plaque
  5. Alzheimer Disease (Alzheimer's Disease)
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Key Therapies for Kuru

Efficacy Chart >>
  1. Transplants (Transplant) : 4 results
  2. Dilatation and Curettage (D&C) : 1 result

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