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Inappropriate ADH Syndrome (SIADH) Summary

Description: A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.

Also Known As: SIADH; Syndrome of Inappropriate ADH (SIADH) Secretion; ADH Syndrome, Inappropriate; Schwartz Bartter Syndrome; Syndrome, Inappropriate ADH Show All >>

Networked: 1069 relevant articles (46 outcomes, 47 trials/studies) for this Disease

Key Drugs and Agents for Inappropriate ADH Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Hormones : 10 outcomes 23 studies in 889 results : IBA
  2. Urea (Carbamide) : 8 outcomes 4 studies in 25 results : FDA 6 Generic
  3. tolvaptan : 6 outcomes 7 studies in 34 results : FDA 1
  4. Sodium : 4 outcomes 7 studies in 159 results : IBA
  5. Vasopressin Receptors (Arginine Vasopressin Receptor) : 3 outcomes 4 studies in 25 results : IBA
  6. Uric Acid (Urate) : 3 outcomes 3 studies in 30 results : IBA
  7. Vasopressins (Vasopressin) : 2 outcomes 2 studies in 57 results : IBA
  8. Deamino Arginine Vasopressin (Desmopressin) : 2 outcomes 1 study in 20 results : FDA 16 Generic
  9. VP 343 : 2 outcomes 1 study in 2 results : IBA
  10. Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics) : 2 outcomes in 6 results : IBA
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Diseases Related to Inappropriate ADH Syndrome

  1. Hyponatremia
  2. Neoplasms (Cancer)
  3. Heart Failure
  4. Wasting Syndrome (Wasting Disease)
  5. Craniocerebral Trauma (Head Injury)
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Key Therapies for Inappropriate ADH Syndrome

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 4 outcomes in 36 results
  2. Radiotherapy : 1 outcome in 3 results
  3. Combination Drug Therapy (Combination Chemotherapy) : 1 outcome in 3 results
  4. Fluid Therapy (Oral Rehydration Therapy) : 1 study in 8 results
  5. Neck Dissection (Radical Neck Dissection) : 1 study in 4 results
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