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Heart Failure Summary

Description: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Also Known As: Congestive Heart Failure; Heart Failure, Congestive; Heart Failure, Left-Sided; Heart Failure, Right-Sided; Left-Sided Heart Failure Show All >>

Networked: 51413 relevant articles (3954 outcomes, 8286 trials/studies) for this Disease

Key Drugs and Agents for Heart Failure

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors) : 256 outcomes 421 studies in 2278 results : IBA
  2. Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme) : 139 outcomes 281 studies in 1544 results : IBA
  3. Brain Natriuretic Peptide (Natrecor) : 125 outcomes 369 studies in 2186 results : FDA 1
  4. carvedilol (Coreg) : 123 outcomes 294 studies in 754 results : FDA 18 Generic
  5. Diuretics : 115 outcomes 151 studies in 1384 results : IBA
  6. Digoxin (Digitek) : 100 outcomes 191 studies in 1045 results : FDA 18 Generic
  7. Captopril (Capoten) : 87 outcomes 165 studies in 734 results : FDA 30 Generic
  8. Spironolactone (Aldactone) : 70 outcomes 157 studies in 489 results : FDA 38 Generic
  9. Enalapril : 61 outcomes 161 studies in 499 results : FDA 28 Generic
  10. tolvaptan : 61 outcomes 77 studies in 159 results : FDA 1
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Diseases Related to Heart Failure

  1. Hypertension (High Blood Pressure)
  2. Myocardial Infarction
  3. Heart Failure
  4. Left Ventricular Dysfunction
  5. Stroke (Strokes)
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Key Therapies for Heart Failure

Efficacy Chart >>
  1. Cardiac Resynchronization Therapy : 272 outcomes 314 studies in 2087 results
  2. Heart Transplantation (Grafting, Heart) : 170 outcomes 114 studies in 2066 results
  3. Transplantation (Transplant Recipients) : 71 outcomes 75 studies in 980 results
  4. Drug Therapy (Chemotherapy) : 64 outcomes 96 studies in 874 results
  5. Transplants (Transplant) : 55 outcomes 68 studies in 1067 results
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