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Cardiomegaly (Heart Hypertrophy) Summary

Description: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Also Known As: Heart Hypertrophy; Enlarged Heart; Heart Enlargement; Enlargement, Heart; Heart, Enlarged Show All >>

Networked: 6204 relevant articles (301 outcomes, 751 trials/studies) for this Disease

Key Drugs and Agents for Cardiomegaly

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Angiotensin II : 14 outcomes 56 studies in 456 results : IBA
  2. Captopril (Capoten) : 9 outcomes 6 studies in 70 results : FDA 30 Generic
  3. Atrial Natriuretic Factor (ANF) : 7 outcomes 19 studies in 231 results : IBA
  4. Collagen : 7 outcomes 11 studies in 169 results : IBA
  5. Losartan (Cozaar) : 7 outcomes 9 studies in 72 results : FDA 24 Generic
  6. Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors) : 7 outcomes 8 studies in 68 results : IBA
  7. Isoproterenol (Isoprenaline) : 6 outcomes 45 studies in 285 results : FDA 22 Generic
  8. Messenger RNA (mRNA) : 6 outcomes 22 studies in 235 results : IBA
  9. Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme) : 6 outcomes 22 studies in 113 results : IBA
  10. Adiponectin : 6 outcomes 1 study in 23 results : IBA
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Diseases Related to Cardiomegaly

  1. Fibrosis (Cirrhosis)
  2. Hypertension (High Blood Pressure)
  3. Heart Failure
  4. Body Weight (Weight, Body)
  5. Hypertrophy
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Key Therapies for Cardiomegaly

Efficacy Chart >>
  1. Aftercare (After-Treatment) : 7 outcomes 2 studies in 21 results
  2. Transplants (Transplant) : 3 outcomes 1 study in 18 results
  3. Ligation : 2 outcomes 1 study in 31 results
  4. Homologous Transplantation (Allograft) : 2 outcomes in 6 results
  5. Renal Dialysis (Hemodialysis) : 1 outcome 3 studies in 25 results
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