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Glioblastoma (Glioblastoma Multiforme) Summary

Description: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Also Known As: Glioblastoma Multiforme; Grade IV Astrocytoma; Astrocytomas, Grade IV; Giant Cell Glioblastomas; Glioblastoma, Giant Cell Show All >>

Networked: 11830 relevant articles (637 outcomes, 2047 trials/studies) for this Disease

Key Drugs and Agents for Glioblastoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. temozolomide (Temodar) : 129 outcomes 276 studies in 1188 results : FDA 3 Generic
  2. bevacizumab : 46 outcomes 117 studies in 394 results : FDA 2
  3. irinotecan (Camptosar) : 20 outcomes 40 studies in 84 results : FDA 19 Generic
  4. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor) : 17 outcomes 58 studies in 325 results : IBA
  5. Carmustine (FIVB) : 12 outcomes 40 studies in 186 results : FDA 2
  6. DNA (Deoxyribonucleic Acid) : 10 outcomes 43 studies in 429 results : IBA
  7. Epidermal Growth Factor Receptor (EGF Receptor) : 9 outcomes 39 studies in 484 results : IBA
  8. Paclitaxel (Taxol) : 9 outcomes 20 studies in 83 results : FDA 13 Generic
  9. Carboplatin (JM8) : 8 outcomes 22 studies in 52 results : FDA 29 Generic
  10. Phosphotransferases (Kinase) : 7 outcomes 29 studies in 275 results : IBA
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Diseases Related to Glioblastoma

  1. Neoplasms (Cancer)
  2. Glioma (Gliomas)
  3. Astrocytoma (Pilocytic Astrocytoma)
  4. Glioblastoma (Glioblastoma Multiforme)
  5. Brain Neoplasms (Brain Tumor)
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Key Therapies for Glioblastoma

Efficacy Chart >>
  1. Radiotherapy : 73 outcomes 209 studies in 1032 results
  2. Drug Therapy (Chemotherapy) : 72 outcomes 147 studies in 1074 results
  3. Heterologous Transplantation (Xenotransplantation) : 41 outcomes 75 studies in 615 results
  4. Immunotherapy : 16 outcomes 28 studies in 174 results
  5. Boron Neutron Capture Therapy : 6 outcomes 22 studies in 77 results
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