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Glioblastoma (Glioblastoma Multiforme) Summary

5326 relevant articles (223 outcomes, 847 trials/studies) found for this Disease

Description: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Also Known As: Glioblastoma Multiforme; Grade IV Astrocytoma; Astrocytomas, Grade IV; Giant Cell Glioblastomas; Glioblastoma, Giant Cell Show All >>

Key Drugs and Agents for Glioblastoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. temozolomide (Temodar) : 35 outcomes 65 studies in 222 results : FDA 1
  2. Carmustine (FIVB) : 9 outcomes 29 studies in 131 results : FDA 2
  3. Epidermal Growth Factor Receptor (EGF Receptor) : 5 outcomes 27 studies in 253 results : IBA
  4. Procarbazine (Matulane) : 5 outcomes 14 studies in 38 results : FDA 1
  5. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor) : 4 outcomes 20 studies in 142 results : IBA
  6. Carboplatin (JM8) : 4 outcomes 14 studies in 36 results : FDA 23 Generic
  7. Etoposide (VP 16) : 4 outcomes 10 studies in 43 results : FDA 16 Generic
  8. Immunotoxins (Immunotoxin) : 4 outcomes 1 study in 17 results : IBA
  9. Vincristine (Oncovin) : 3 outcomes 15 studies in 46 results : FDA 18 Generic
  10. DNA (Deoxyribonucleic Acid) : 3 outcomes 13 studies in 247 results : IBA
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Diseases Related to Glioblastoma

  1. Neoplasms (Cancer)
  2. Astrocytoma (Pilocytic Astrocytoma)
  3. Glioma (Gliomas)
  4. Glioblastoma (Glioblastoma Multiforme)
  5. Oligodendroglioma
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Key Therapies for Glioblastoma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 34 outcomes 74 studies in 460 results
  2. Heterologous Transplantation (Xenotransplantation) : 12 outcomes 30 studies in 237 results
  3. Immunotherapy : 3 outcomes 10 studies in 54 results
  4. Adjuvant Chemotherapy : 3 outcomes 5 studies in 29 results
  5. Boron Neutron Capture Therapy : 2 outcomes 18 studies in 57 results
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