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Tourette Syndrome (Tourette's Syndrome) Summary

Description: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or a general medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)

Also Known As: Tourette's Syndrome; Combined Vocal and Multiple Motor Tic Disorder; Gilles de la Tourette Syndrome; Tourette's Disorder; Syndrome, Tourette's Show All >>

Networked: 1209 relevant articles (95 outcomes, 192 trials/studies) for this Disease

Key Drugs and Agents for Tourette Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Haloperidol (Haldol) : 12 outcomes 16 studies in 102 results : FDA 107 Generic
  2. Pimozide (Orap) : 9 outcomes 10 studies in 38 results : FDA 1
  3. Nicotine : 7 outcomes 9 studies in 46 results : FDA 9
  4. Clonidine (ST 155) : 7 outcomes 4 studies in 55 results : FDA 55 Generic
  5. aripiprazole (Abilify) : 6 outcomes 10 studies in 35 results : FDA 4
  6. Risperidone (Risperdal Consta) : 6 outcomes 8 studies in 25 results : FDA 35 Generic
  7. Antipsychotic Agents (Antipsychotics) : 6 outcomes 5 studies in 55 results : IBA
  8. etiracetam (levetiracetam) : 3 outcomes 3 studies in 8 results : FDA 45 Generic
  9. atomoxetine (Strattera) : 3 outcomes 1 study in 9 results : FDA 10 Generic
  10. Carbon Monoxide : 2 outcomes 10 studies in 73 results : IBA
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Diseases Related to Tourette Syndrome

  1. Tics (Tic)
  2. Tic Disorders (Tic Disorder)
  3. Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
  4. Schizophrenia (Dementia Praecox)
  5. Bipolar Disorder (Mania)
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Key Therapies for Tourette Syndrome

Efficacy Chart >>
  1. Deep Brain Stimulation : 8 outcomes 14 studies in 117 results
  2. Transdermal Patch : 2 outcomes in 2 results
  3. Psychosurgery (Lobotomy) : 1 outcome 1 study in 10 results
  4. Injections : 1 outcome 1 study in 3 results
  5. Neurofeedback : 1 outcome in 3 results
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