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Fibromyalgia (Fibrositis) Summary

Description: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)

Also Known As: Fibrositis; Fibromyalgia, Primary; Fibromyalgia, Secondary; Fibromyalgia-Fibromyositis Syndrome; Fibromyositis-Fibromyalgia Syndrome Show All >>

Networked: 2104 relevant articles (279 outcomes, 544 trials/studies) for this Disease

Key Drugs and Agents for Fibromyalgia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. duloxetine (Cymbalta) : 33 outcomes 51 studies in 133 results : FDA 10
  2. pregabalin (Lyrica) : 31 outcomes 42 studies in 144 results : FDA 5
  3. milnacipran (Ixel) : 29 outcomes 35 studies in 94 results : FDA 1
  4. Serotonin (5 Hydroxytryptamine) : 16 outcomes 27 studies in 131 results : IBA
  5. Antidepressive Agents (Antidepressants) : 12 outcomes 9 studies in 66 results : IBA
  6. Norepinephrine (Noradrenaline) : 11 outcomes 10 studies in 66 results : FDA 5 Generic
  7. Amitriptyline (Elavil) : 10 outcomes 17 studies in 51 results : FDA 198 Generic
  8. tropisetron (Navoban) : 8 outcomes 8 studies in 23 results : IBA
  9. salicylhydroxamic acid (SHAM) : 5 outcomes 9 studies in 24 results : IBA
  10. venlafaxine (Effexor) : 5 outcomes 6 studies in 17 results : FDA 18 Generic
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Diseases Related to Fibromyalgia

  1. Pain (Aches)
  2. Neuralgia (Stump Neuralgia)
  3. Fatigue
  4. Major Depressive Disorder (Major Depressive Disorders)
  5. Low Back Pain (Lumbago)
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Key Therapies for Fibromyalgia

Efficacy Chart >>
  1. Psychology Biofeedback (Biofeedback) : 6 outcomes 5 studies in 14 results
  2. Balneology : 5 outcomes 9 studies in 21 results
  3. Drug Therapy (Chemotherapy) : 5 outcomes 6 studies in 48 results
  4. Massage (Reflexology) : 4 outcomes 12 studies in 23 results
  5. Transcutaneous Electric Nerve Stimulation (TENS) : 4 outcomes 4 studies in 11 results
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