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Multiple Hereditary Exostoses (Hereditary Multiple Exostoses) Summary

55 relevant articles (0 outcomes, 3 trials/studies) found for this Disease

Description: Hereditary disorder transmitted by an autosomal dominant gene and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones. The genetic abnormality results in a defect in the osteoclastic activity at the metaphyseal ends of the bone during the remodeling process in childhood or early adolescence. The metaphyses develop benign, bony outgrowths often capped by cartilage. A small number undergo neoplastic transformation.

Also Known As: Hereditary Multiple Exostoses; Exostoses, Multiple; Hereditary Exostoses, Multiple; Multiple Cartilaginous Exostoses; Multiple Exostoses Show All >>

Key Drugs and Agents for Multiple Hereditary Exostoses

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Carbon Monoxide : 2 studies in 3 results : IBA
  2. Cyclin-Dependent Kinase Inhibitor p15 : 1 study in 1 result : IBA
  3. Messenger RNA (mRNA) : 1 study in 1 result : IBA
  4. Insulin (Novolin) : 1 study in 1 result : FDA 2
  5. Carrier Proteins (Binding Protein) : 1 study in 1 result : IBA
  6. zinc-binding protein (zinc binding protein) : 1 study in 1 result : IBA
  7. Heparitin Sulfate (Heparan Sulfate) : 9 results : IBA
  8. Glycosyltransferases : 7 results : IBA
  9. Proteins (Proteins, Gene) : 4 results : IBA
  10. Complementary DNA (cDNA) : 3 results : IBA
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Diseases Related to Multiple Hereditary Exostoses

  1. Syndrome
  2. Obesity
  3. Neoplasms (Cancer)
  4. Osteochondroma (Osteocartilaginous Exostosis)
  5. Langer-Giedion Syndrome (Trichorhinophalangeal Syndrome Type II)
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Key Therapies for Multiple Hereditary Exostoses

Efficacy Chart >>
  1. Osteotomy : 5 results
  2. Decompression : 3 results
  3. Ligation : 2 results
  4. Distraction Osteogenesis : 1 result
  5. Transplants (Transplant) : 1 result
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