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Estradiol (Estrace) Summary

Description: Generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. In humans, it is produced primarily by the cyclic ovaries and the PLACENTA. It is also produced by the adipose tissue of men and postmenopausal women. The 17-alpha-isomer of estradiol binds weakly to estrogen receptors (RECEPTORS, ESTROGEN) and exhibits little estrogenic activity in estrogen-responsive tissues. Various isomers can be synthesized.

Also Known As: Estrace; Oestradiol; 17 beta-Oestradiol; Aerodiol; Estraderm TTS Show All >>

Networked: 10364 relevant articles (363 outcomes, 1195 trials/studies) for this Drug

Key Diseases for which Estradiol is Relevant

  1. Neoplasms (Cancer) : 33 outcomes 131 studies in 1467 results
  2. Breast Neoplasms (Breast Cancer) : 28 outcomes 225 studies in 1796 results
  3. Hemorrhage : 18 outcomes 31 studies in 238 results
  4. Ischemia : 17 outcomes 9 studies in 82 results
  5. Osteoporosis : 16 outcomes 28 studies in 176 results
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Drugs Related to Estradiol

  1. Estrogens (Estrogen)
  2. Progesterone
  3. Testosterone (Sustanon)
  4. Hormones
  5. Tamoxifen
  6. Estrone (Folliculin)
  7. Prolactin
  8. Insulin (Novolin)
  9. Cyproterone Acetate
  10. Follicle Stimulating Hormone (Follitropin)
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Therapies Related to Estradiol

  1. Hormone Replacement Therapy (Therapy, Hormone Replacement)
  2. Female Contraceptive Devices (Vaginal Ring)
  3. Ovariectomy (Oophorectomy)
  4. Estrogen Replacement Therapy
  5. Drug Therapy (Chemotherapy)
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