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Temporal Lobe Epilepsy Summary

Description: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic (i.e., related to an identified disease process or lesion). (From Adams et al., Principles of Neurology, 6th ed, p321)

Also Known As: Epilepsy, Temporal Lobe; Benign Psychomotor Epilepsy, Childhood; Childhood Benign Psychomotor Epilepsy; Epilepsy, Lateral Temporal; Epilepsy, Uncinate Show All >>

Networked: 2168 relevant articles (42 outcomes, 355 trials/studies) for this Disease

Key Drugs and Agents for Temporal Lobe Epilepsy

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Carbamazepine (Tegretol) : 7 outcomes 4 studies in 40 results : FDA 24 Generic
  2. Anticonvulsants (Antiepileptic Drugs) : 5 outcomes 11 studies in 62 results : IBA
  3. Kainic Acid (Kainate) : 4 outcomes 41 studies in 227 results : IBA
  4. topiramate (Topamax) : 3 outcomes 2 studies in 15 results : FDA 28 Generic
  5. Valproic Acid (Valproate, Semisodium) : 3 outcomes 1 study in 9 results : FDA 51 Generic
  6. Vigabatrin : 3 outcomes 1 study in 8 results : FDA 2
  7. zonisamide (Zonegran) : 3 outcomes 1 study in 3 results : FDA 19 Generic
  8. lamotrigine (Lamictal) : 3 outcomes in 8 results : FDA 33 Generic
  9. gabapentin (Neurontin) : 3 outcomes in 4 results : FDA 37 Generic
  10. Protons (Proton) : 2 outcomes 19 studies in 72 results : IBA
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Diseases Related to Temporal Lobe Epilepsy

  1. Seizures (Seizure)
  2. Epilepsy (Aura)
  3. Partial Epilepsies (Epilepsy, Partial)
  4. Sclerosis
  5. Status Epilepticus (Complex Partial Status Epilepticus)
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Key Therapies for Temporal Lobe Epilepsy

Efficacy Chart >>
  1. Anterior Temporal Lobectomy : 5 outcomes 13 studies in 104 results
  2. Psychology Biofeedback (Biofeedback) : 2 outcomes 1 study in 3 results
  3. Vagus Nerve Stimulation : 2 outcomes in 6 results
  4. Relaxation Therapy : 2 outcomes in 2 results
  5. Electrodes (Electrode) : 1 outcome 23 studies in 158 results
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