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Generalized Epilepsy Summary

Description: Recurrent conditions characterized by epileptic seizures which arise diffusely and simultaneously from both hemispheres of the brain. Classification is generally based upon motor manifestations of the seizure (e.g., convulsive, nonconvulsive, akinetic, atonic, etc.) or etiology (e.g., idiopathic, cryptogenic, and symptomatic). (From Mayo Clin Proc, 1996 Apr;71(4):405-14)

Also Known As: Epilepsy, Generalized; Convulsive Seizure Disorder, Generalized; Epilepsy, Akinetic; Epilepsy, Atonic; Generalized Convulsive Epilepsy Show All >>

Networked: 1060 relevant articles (58 outcomes, 149 trials/studies) for this Disease

Key Drugs and Agents for Generalized Epilepsy

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Lennox-Gastaut type Epileptic encephalopathy : 11 outcomes 8 studies in 72 results : IBA
  2. lamotrigine (Lamictal) : 11 outcomes 8 studies in 55 results : FDA 33 Generic
  3. Valproic Acid (Valproate, Semisodium) : 9 outcomes 14 studies in 99 results : FDA 51 Generic
  4. Anticonvulsants (Antiepileptic Drugs) : 7 outcomes 9 studies in 69 results : IBA
  5. topiramate (Topamax) : 7 outcomes 3 studies in 26 results : FDA 28 Generic
  6. Immunoglobulin E (IgE) : 5 outcomes 67 studies in 366 results : IBA
  7. zonisamide (Zonegran) : 5 outcomes 2 studies in 18 results : FDA 19 Generic
  8. etiracetam (levetiracetam) : 4 outcomes 7 studies in 33 results : FDA 45 Generic
  9. Carbamazepine (Tegretol) : 2 outcomes 4 studies in 33 results : FDA 24 Generic
  10. lacosamide : 2 outcomes 1 study in 5 results : FDA 3
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Diseases Related to Generalized Epilepsy

  1. Seizures (Seizure)
  2. Epilepsy (Aura)
  3. Partial Epilepsies (Epilepsy, Partial)
  4. Absence Epilepsy (Absence Seizure)
  5. Juvenile Myoclonic Epilepsy
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Key Therapies for Generalized Epilepsy

Efficacy Chart >>
  1. Ketogenic Diet : 1 outcome 1 study in 3 results
  2. Carbohydrate-Restricted Diet (Low Carbohydrate Diet) : 1 outcome in 2 results
  3. Deep Brain Stimulation : 1 outcome in 2 results
  4. Vagus Nerve Stimulation : 2 studies in 9 results
  5. Palliative Care (Palliative Medicine) : 1 study in 2 results
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