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Ependymoma Summary

563 relevant articles (9 outcomes, 63 trials/studies) found for this Disease

Description: Glioma derived from ependymocytes that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9)

Also Known As: Anaplastic Ependymoma; Cellular Ependymoma; Clear Cell Ependymoma; Papillary Ependymoma; Anaplastic Ependymomas Show All >>

Key Drugs and Agents for Ependymoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Etoposide (VP 16) : 2 outcomes 5 studies in 15 results : FDA 16 Generic
  2. Carboplatin (JM8) : 1 outcome 1 study in 4 results : FDA 23 Generic
  3. Cisplatin (Platino) : 1 outcome in 4 results : FDA 6 Generic
  4. temozolomide (Temodar) : 1 outcome in 3 results : FDA 1
  5. Vincristine (Oncovin) : 6 studies in 10 results : FDA 18 Generic
  6. Glial Fibrillary Acidic Protein : 5 studies in 33 results : IBA
  7. Lomustine (CCNU) : 5 studies in 9 results : FDA 1
  8. Proteins (Proteins, Gene) : 3 studies in 17 results : IBA
  9. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor) : 3 studies in 7 results : IBA
  10. DNA (Deoxyribonucleic Acid) : 2 studies in 38 results : IBA
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Diseases Related to Ependymoma

  1. Medulloblastoma
  2. Astrocytoma (Pilocytic Astrocytoma)
  3. Neoplasms (Cancer)
  4. Brain Neoplasms (Brain Tumor)
  5. Glioblastoma (Glioblastoma Multiforme)
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Key Therapies for Ependymoma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 6 outcomes 15 studies in 72 results
  2. Aftercare (After-Treatment) : 1 outcome in 5 results
  3. Salvage Therapy : 1 outcome in 3 results
  4. Adjuvant Chemotherapy : 4 studies in 13 results
  5. Heterologous Transplantation (Xenotransplantation) : 1 study in 13 results
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