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Diabetic Neuropathies (Diabetic Neuropathy) Summary

Description: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Also Known As: Diabetic Neuropathy; Neuropathy, Diabetic; Diabetic Amyotrophy; Diabetic Polyneuropathy; Asymmetric Diabetic Proximal Motor Neuropathy Show All >>

Networked: 2646 relevant articles (304 outcomes, 523 trials/studies) for this Disease

Key Drugs and Agents for Diabetic Neuropathies

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Aldehyde Reductase (Aldose Reductase) : 24 outcomes 29 studies in 140 results : IBA
  2. gabapentin (Neurontin) : 21 outcomes 21 studies in 84 results : FDA 37 Generic
  3. Thioctic Acid (Lipoic Acid) : 19 outcomes 25 studies in 101 results : IBA
  4. pregabalin (Lyrica) : 14 outcomes 21 studies in 61 results : FDA 5
  5. Insulin (Novolin) : 12 outcomes 21 studies in 148 results : FDA 2
  6. Capsaicin (Zostrix) : 9 outcomes 14 studies in 40 results : FDA 1
  7. sorbinil : 9 outcomes 9 studies in 26 results : IBA
  8. Streptozocin (Streptozotocin) : 8 outcomes 37 studies in 197 results : FDA 1
  9. Nerve Growth Factor (NGF) : 8 outcomes 10 studies in 77 results : IBA
  10. ONO 2235 (epalrestat) : 8 outcomes 4 studies in 31 results : IBA
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Diseases Related to Diabetic Neuropathies

  1. Pain (Aches)
  2. Neuralgia (Stump Neuralgia)
  3. Postherpetic Neuralgia
  4. Fibromyalgia (Fibrositis)
  5. Diabetic Neuropathies (Diabetic Neuropathy)
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Key Therapies for Diabetic Neuropathies

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 4 outcomes 5 studies in 35 results
  2. Transcutaneous Electric Nerve Stimulation (TENS) : 4 outcomes 4 studies in 10 results
  3. Decompression : 3 outcomes 6 studies in 23 results
  4. Transplantation (Transplant Recipients) : 2 outcomes 2 studies in 27 results
  5. Intramuscular Injections : 2 outcomes 2 studies in 3 results
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