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Desipramine (Pertofrane) Summary

Description: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.

Also Known As: Pertofrane; Norpramin; Apo-Desipramine; Apotex Brand of Desipramine Hydrochloride; Aventis Behring Brand of Desipramine Hydrochloride Show All >>

Networked: 709 relevant articles (66 outcomes, 121 trials/studies) for this Drug

Key Diseases for which Desipramine is Relevant

  1. Pain (Aches) : 6 outcomes 5 studies in 38 results
  2. Neuralgia (Stump Neuralgia) : 6 outcomes 2 studies in 17 results
  3. Panic Disorder (Panic Attack) : 5 outcomes 4 studies in 12 results
  4. Cocaine-Related Disorders (Cocaine Addiction) : 4 outcomes 4 studies in 20 results
  5. Tics (Tic) : 4 outcomes 2 studies in 7 results
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Drugs Related to Desipramine

  1. Amitriptyline (Elavil)
  2. Tricyclic Antidepressive Agents (Tricyclic Antidepressants)
  3. Clomipramine (Anafranil)
  4. Imipramine (Janimine)
  5. Fluoxetine (Prozac)
  6. Serotonin (5 Hydroxytryptamine)
  7. Nortriptyline (Aventyl)
  8. Antidepressive Agents (Antidepressants)
  9. Methadone (Dolophine)
  10. Cocaine (Cocaine HCl)
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Therapies Related to Desipramine

  1. Analgesia
  2. Ligation
  3. Oral Administration
  4. Aftercare (After-Treatment)
  5. Induced Hypothermia
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