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Deoxycytidine Kinase Summary

Description: An enzyme that catalyzes reversibly the phosphorylation of deoxycytidine with the formation of a nucleoside diphosphate and deoxycytidine monophosphate. Cytosine arabinoside can also act as an acceptor. All natural nucleoside triphosphates, except deoxycytidine triphosphate, can act as donors. The enzyme is induced by some viruses, particularly the herpes simplex virus (HERPESVIRUS HOMINIS). EC 2.7.1.74.

Also Known As: Kinase, Deoxycytidine; NTP:deoxycytidine 5'-phosphotransferase

Networked: 150 relevant articles (2 outcomes, 15 trials/studies) for this Bio-Agent

Key Diseases for which Deoxycytidine Kinase is Relevant

  1. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) : 1 outcome 1 study in 7 results
  2. Lymphoma (Lymphomas) : 1 outcome 1 study in 2 results
  3. Neoplasms (Cancer) : 5 studies in 47 results
  4. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) : 2 studies in 7 results
  5. Acute Myeloid Leukemia (Acute Myelogenous Leukemia) : 1 study in 17 results
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Drugs Related to Deoxycytidine Kinase

  1. Cladribine
  2. 5'-Nucleotidase (5' Nucleotidase)
  3. bryostatin 1
  4. gemcitabine
  5. fludarabine
  6. Cytidine Deaminase
  7. Ribonucleotide Reductases (Ribonucleotide Reductase)
  8. DNA (Deoxyribonucleic Acid)
  9. DCMP Deaminase (Deoxycytidylate Deaminase)
  10. Thymidine
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Therapies Related to Deoxycytidine Kinase

  1. Drug Therapy (Chemotherapy)
  2. Cell Transplantation
  3. Cystectomy
  4. Heterologous Transplantation (Xenotransplantation)
  5. Remission Induction
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