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Dapsone Summary

Description: A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)

Also Known As: 4,4'-Diaminophenyl Sulfone; Avlosulfone; DADPS; Dapsoderm-X; Dapson-Fatol Show All >>

Networked: 1722 relevant articles (165 outcomes, 165 trials/studies) for this Drug

Key Diseases for which Dapsone is Relevant

  1. Acne Vulgaris : 15 outcomes 11 studies in 47 results
  2. Leprosy (Hansen's Disease) : 13 outcomes 42 studies in 389 results
  3. Infection : 9 outcomes 8 studies in 69 results
  4. Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia) : 8 outcomes 11 studies in 89 results
  5. Vasculitis (Vasculitides) : 6 outcomes 3 studies in 40 results
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Drugs Related to Dapsone

  1. Rifampin (Rifampicin)
  2. Pyrimethamine (Daraprim)
  3. Pentamidine (NebuPent)
  4. Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)
  5. Trimethoprim (Proloprim)
  6. Colchicine
  7. Immunoglobulin A (IgA)
  8. Primaquine
  9. Adrenal Cortex Hormones (Corticosteroids)
  10. Chloroquine (Aralen)
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Therapies Related to Dapsone

  1. Injections
  2. Renal Dialysis (Hemodialysis)
  3. Drug Therapy (Chemotherapy)
  4. Mesotherapy
  5. Chemoprevention
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