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Electron Transport Complex IV (Cytochrome c Oxidase) Summary

Description: A multisubunit enzyme complex containing CYTOCHROME A GROUP; CYTOCHROME A3; two copper atoms; and 13 different protein subunits. It is the terminal oxidase complex of the RESPIRATORY CHAIN and collects electrons that are transferred from the reduced CYTOCHROME C GROUP and donates them to molecular OXYGEN, which is then reduced to water. The redox reaction is simultaneously coupled to the transport of PROTONS across the inner mitochondrial membrane.

Also Known As: Cytochrome c Oxidase; Oxidase, Cytochrome; Cytochrome-c Oxidase (Complex IV); Cytochrome Oxidase; Bacterial Electron Transport Complex IV Show All >>

Networked: 1505 relevant articles (24 outcomes, 132 trials/studies) for this Bio-Agent

Key Diseases for which Electron Transport Complex IV is Relevant

  1. Anoxia (Hypoxia) : 5 outcomes 10 studies in 183 results
  2. Muscular Diseases (Myopathy) : 3 outcomes 3 studies in 42 results
  3. Polymyositis : 3 outcomes in 6 results
  4. Ischemia : 2 outcomes 1 study in 63 results
  5. Body Weight (Weight, Body) : 2 outcomes in 34 results
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Drugs Related to Electron Transport Complex IV

  1. Zidovudine (Retrovir)
  2. Adenosine Triphosphate (ATP)
  3. I-antigen
  4. NAD (NADH)
  5. Glutathione (Reduced Glutathione)
  6. Carbon Monoxide
  7. NADH Dehydrogenase
  8. Superoxide Dismutase
  9. Adenosine Diphosphate (ADP)
  10. Oxygen
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Therapies Related to Electron Transport Complex IV

  1. Lenses
  2. Carotid Endarterectomy
  3. Intraoperative Period
  4. Ligation
  5. Heterologous Transplantation (Xenotransplantation)
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