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Craniopharyngioma (Craniopharyngiomas) Summary

Description: A benign pituitary-region neoplasm that originates from Rathke's pouch. The two major histologic and clinical subtypes are adamantinous (or classical) craniopharyngioma and papillary craniopharyngioma. The adamantinous form presents in children and adolescents as an expanding cystic lesion in the pituitary region. The cystic cavity is filled with a black viscous substance and histologically the tumor is composed of adamantinomatous epithelium and areas of calcification and necrosis. Papillary craniopharyngiomas occur in adults, and histologically feature a squamous epithelium with papillations. (From Joynt, Clinical Neurology, 1998, Ch14, p50)

Also Known As: Craniopharyngiomas; Craniopharyngioma, Adult; Craniopharyngioma, Child; Neoplasm, Rathke Cleft; Neoplasm, Rathke's Cleft Show All >>

Networked: 773 relevant articles (30 outcomes, 67 trials/studies) for this Disease

Key Drugs and Agents for Craniopharyngioma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Interferon-alpha (Interferon Alfa) : 3 outcomes 4 studies in 7 results : FDA 2
  2. Growth Hormone (Somatotropin) : 2 outcomes 4 studies in 56 results : IBA
  3. Interferons : 2 outcomes 2 studies in 6 results : IBA
  4. Bleomycin (Blenoxane) : 1 outcome 4 studies in 32 results : FDA 7 Generic
  5. Colloids (Colloid) : 1 outcome 3 studies in 21 results : IBA
  6. Protons (Proton) : 1 outcome 2 studies in 18 results : IBA
  7. Biological Markers (Surrogate Marker) : 1 outcome 2 studies in 6 results : IBA
  8. tranilast (N 5') : 1 outcome 1 study in 12 results : IBA
  9. papillary Thyroid cancer : 1 outcome 1 study in 2 results : IBA
  10. Prolactin : 1 outcome in 20 results : IBA
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Diseases Related to Craniopharyngioma

  1. Neoplasms (Cancer)
  2. Cysts
  3. Meningioma (Meningiomas)
  4. Glioma (Gliomas)
  5. Astrocytoma (Pilocytic Astrocytoma)
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Key Therapies for Craniopharyngioma

Efficacy Chart >>
  1. Radiotherapy : 10 outcomes 6 studies in 128 results
  2. Drug Therapy (Chemotherapy) : 3 outcomes 3 studies in 22 results
  3. Aftercare (After-Treatment) : 2 outcomes 3 studies in 25 results
  4. Craniotomy : 1 outcome 2 studies in 44 results
  5. Brachytherapy : 2 studies in 8 results
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