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Febrile Seizures (Febrile Seizure) Summary

Description: Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784)

Also Known As: Febrile Seizure; Febrile Convulsions; Seizures, Febrile; Febrile Convulsion Seizure; Febrile Fit Show All >>

Networked: 988 relevant articles (55 outcomes, 151 trials/studies) for this Disease

Key Drugs and Agents for Febrile Seizures

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Diazepam (Valium) : 20 outcomes 23 studies in 82 results : FDA 84 Generic
  2. Phenobarbital (Luminal) : 12 outcomes 15 studies in 92 results : FDA 1
  3. Valproic Acid (Valproate, Semisodium) : 8 outcomes 6 studies in 38 results : FDA 51 Generic
  4. Acetaminophen (Paracetamol) : 3 outcomes 4 studies in 19 results : FDA 409 Generic
  5. Midazolam (Versed) : 3 outcomes 2 studies in 12 results : FDA 31 Generic
  6. Ibuprofen (Motrin) : 2 outcomes 4 studies in 10 results : FDA 197 Generic
  7. Anticonvulsants (Antiepileptic Drugs) : 2 outcomes 3 studies in 41 results : IBA
  8. Antipyretics : 2 outcomes 2 studies in 25 results : IBA
  9. Melatonin : 2 outcomes 2 studies in 7 results : IBA
  10. Zinc : 1 outcome 7 studies in 19 results : IBA
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Diseases Related to Febrile Seizures

  1. Seizures (Seizure)
  2. Epilepsy (Aura)
  3. Fever (Fevers)
  4. Generalized Epilepsy
  5. Infection
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Key Therapies for Febrile Seizures

Efficacy Chart >>
  1. First Aid (Aids, First) : 1 outcome in 4 results
  2. Aftercare (After-Treatment) : 1 outcome in 3 results
  3. Rectal Administration : 1 outcome in 3 results
  4. Intramuscular Injections : 1 outcome in 1 result
  5. Induced Hyperthermia (Thermotherapy) : 5 studies in 26 results
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