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Cockayne Syndrome (Syndrome, Cockayne) Summary

207 relevant articles (0 outcomes, 7 trials/studies) found for this Disease

Description: A syndrome characterized by multiple system abnormalities including DWARFISM; PHOTOSENSITIVITY DISORDERS; PREMATURE AGING; and HEARING LOSS. It is caused by mutations of a number of autosomal recessive genes encoding proteins that involve transcriptional-coupled DNA REPAIR processes. Cockayne syndrome is classified by the severity and age of onset. Type I (classical; CSA) is early childhood onset in the second year of life; type II (congenital; CSB) is early onset at birth with severe symptoms; type III (xeroderma pigmentosum; XP) is late childhood onset with mild symptoms.

Also Known As: Syndrome, Cockayne; Progeria Like Syndrome; Cockayne Syndrome, Group A; Cockayne Syndrome, Group B; Cockayne Syndrome, Group C Show All >>

Key Drugs and Agents for Cockayne Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Proteins (Proteins, Gene) : 3 studies in 28 results : IBA
  2. DNA (Deoxyribonucleic Acid) : 1 study in 58 results : IBA
  3. Pyrimidine Dimers : 1 study in 6 results : IBA
  4. Interferon-beta : 1 study in 4 results : IBA
  5. Ubiquitin : 1 study in 3 results : IBA
  6. DNA-Formamidopyrimidine Glycosylase (Formamidopyrimidine DNA Glycosylase) : 1 study in 2 results : IBA
  7. bcl-2-Associated X Protein (bcl 2 Associated X Protein) : 1 study in 1 result : IBA
  8. Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1) : 1 study in 1 result : IBA
  9. RNA Polymerase II (RNA Polymerase B) : 20 results : IBA
  10. RNA (Ribonucleic Acid) : 12 results : IBA
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Diseases Related to Cockayne Syndrome

  1. Syndrome
  2. Xeroderma Pigmentosum (Kaposi's Disease)
  3. Progeria (Hutchinson Gilford Syndrome)
  4. Neoplasms (Cancer)
  5. Werner Syndrome (Werner's Syndrome)
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Key Therapies for Cockayne Syndrome

Efficacy Chart >>
  1. Deep Brain Stimulation : 1 result
  2. Cochlear Implantation : 1 result
  3. Heterologous Transplantation (Xenotransplantation) : 1 result
  4. Ligation : 1 result
  5. Drug Therapy (Chemotherapy) : 1 result
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