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Cluster Headache (Cluster Headaches) Summary

Description: A primary headache disorder that is characterized by severe, strictly unilateral PAIN which is orbital, supraorbital, temporal or in any combination of these sites, lasting 15-180 min. occurring 1 to 8 times a day. The attacks are associated with one or more of the following, all of which are ipsilateral: conjunctival injection, lacrimation, nasal congestion, rhinorrhea, facial SWEATING, eyelid EDEMA, and miosis. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Also Known As: Cluster Headaches; Headaches, Cluster; Cluster Headache Syndrome; Syndrome, Horton; Headache, Cluster Show All >>

Networked: 884 relevant articles (146 outcomes, 144 trials/studies) for this Disease

Key Drugs and Agents for Cluster Headache

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Sumatriptan (Imigran) : 27 outcomes 19 studies in 94 results : FDA 32 Generic
  2. Oxygen : 18 outcomes 14 studies in 77 results : IBA
  3. Lithium : 6 outcomes 3 studies in 52 results : IBA
  4. Tryptamines (Triptans) : 6 outcomes 2 studies in 30 results : IBA
  5. Ergotamine (Ergotamine Tartrate) : 6 outcomes 2 studies in 23 results : FDA 11 Generic
  6. Melatonin : 5 outcomes 8 studies in 23 results : IBA
  7. zolmitriptan (Zomig) : 5 outcomes 3 studies in 16 results : FDA 3
  8. topiramate (Topamax) : 4 outcomes 5 studies in 15 results : FDA 28 Generic
  9. Capsaicin (Zostrix) : 4 outcomes 3 studies in 9 results : FDA 1
  10. Lithium Carbonate (Eskalith) : 4 outcomes 1 study in 13 results : FDA 29 Generic
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Diseases Related to Cluster Headache

  1. Migraine Disorders (Migraine)
  2. Pain (Aches)
  3. Headache (Headaches)
  4. Cluster Headache (Cluster Headaches)
  5. Trigeminal Neuralgia (Tic Douloureux)
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Key Therapies for Cluster Headache

Efficacy Chart >>
  1. Deep Brain Stimulation : 12 outcomes 6 studies in 63 results
  2. Injections : 4 outcomes 3 studies in 18 results
  3. Subcutaneous Injections : 2 outcomes in 7 results
  4. Nerve Block (Nerve Blocks) : 1 outcome 1 study in 10 results
  5. Emergency Treatment : 1 outcome 1 study in 2 results
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