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Cholinesterase Inhibitors (Anticholinesterases) Summary

Description: Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.

Also Known As: Anticholinesterases; Acetylcholinesterase Inhibitors; Anti-Cholinesterases; Anticholinesterase Drugs; Cholinesterase Inhibitors, Irreversible Show All >>

Networked: 1694 relevant articles (170 outcomes, 217 trials/studies) for this Bio-Agent

Key Diseases for which Cholinesterase Inhibitors is Relevant

  1. Alzheimer Disease (Alzheimer's Disease) : 99 outcomes 115 studies in 872 results
  2. Dementia (Dementias) : 36 outcomes 68 studies in 379 results
  3. Myasthenia Gravis : 14 outcomes 3 studies in 80 results
  4. Hallucinations (Hallucination) : 5 outcomes 2 studies in 24 results
  5. Neurobehavioral Manifestations : 5 outcomes 1 study in 24 results
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Drugs Related to Cholinesterase Inhibitors

  1. donepezil (Aricept)
  2. rivastigmine (Exelon)
  3. Galantamine (Galanthamine)
  4. Memantine (Namenda)
  5. Acetylcholine (Acetylcholine Chloride)
  6. Tacrine (Cognex)
  7. Trichlorfon (Metrifonate)
  8. Ginkgo biloba extract 761 (Rokan)
  9. N-Methylaspartate (NMDA)
  10. Neostigmine (Neostigmine Bromide)
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Therapies Related to Cholinesterase Inhibitors

  1. Thymectomy
  2. Activities of Daily Living (ADL)
  3. Drug Therapy (Chemotherapy)
  4. Plasma Exchange
  5. Therapeutics
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