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Cerebroside-Sulfatase (Arylsulfatase A) Summary

Description: An enzyme that catalyzes the hydrolysis of cerebroside 3-sulfate (sulfatide) to yield a cerebroside and inorganic sulfate. A marked deficiency of arylsulfatase A, which is considered the heat-labile component of cerebroside sulfatase, has been demonstrated in all forms of metachromatic leukodystrophy (LEUKODYSTROPHY, METACHROMATIC). EC 3.1.6.8.

Also Known As: Arylsulfatase A; Cerebroside Sulfatase; Sulfatase, Sulfatidate; Sulfatidate Sulfatase; Cerebroside-3-sulfate 3-sulfohydrolase

Networked: 324 relevant articles (7 outcomes, 15 trials/studies) for this Bio-Agent

Key Diseases for which Cerebroside-Sulfatase is Relevant

  1. Metachromatic Leukodystrophy (Sulfatide Lipidosis) : 4 outcomes 8 studies in 248 results
  2. Neoplasms (Cancer) : 1 outcome in 13 results
  3. Nervous System Diseases (Neurological Disorders) : 1 outcome in 3 results
  4. Mucopolysaccharidosis VI (Syndrome, Maroteaux-Lamy) : 1 outcome in 2 results
  5. Memory Disorders (Memory Loss) : 1 outcome in 1 result
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Drugs Related to Cerebroside-Sulfatase

  1. Sulfoglycosphingolipids (Sulfatides)
  2. Enzymes
  3. Lysergic Acid Diethylamide (LSD)
  4. DEAE-Cellulose
  5. Complementary DNA (cDNA)
  6. N-Acetylgalactosamine-4-Sulfatase (Arylsulfatase B)
  7. Arylsulfatases
  8. beta-Galactosidase (Lactaid)
  9. Molecular Chaperones (Chaperone, Molecular)
  10. Interleukin-8 (Interleukin 8)
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Therapies Related to Cerebroside-Sulfatase

  1. Enzyme Replacement Therapy
  2. Transplants (Transplant)
  3. Tissue Therapy (Cell Therapy)
  4. Intravenous Injections
  5. Denervation

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