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Brain Edema (Cerebral Edema) Summary

Description: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Also Known As: Cerebral Edema; Edema, Cerebral; Brain Swelling; Cerebral Edema, Cytotoxic; Cerebral Edema, Vasogenic Show All >>

Networked: 3983 relevant articles (305 outcomes, 508 trials/studies) for this Disease

Key Drugs and Agents for Brain Edema

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Mannitol (Osmitrol) : 22 outcomes 19 studies in 153 results : FDA 28 Generic
  2. Dexamethasone (Maxidex) : 16 outcomes 10 studies in 138 results : FDA 77 Generic
  3. Oxygen : 7 outcomes 7 studies in 93 results : IBA
  4. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor) : 6 outcomes 12 studies in 87 results : IBA
  5. Evans Blue (Blue, Evans) : 6 outcomes 8 studies in 112 results : FDA 1
  6. Methylprednisolone : 6 outcomes 2 studies in 15 results : FDA 18 Generic
  7. Adrenal Cortex Hormones (Corticosteroids) : 5 outcomes 5 studies in 53 results : IBA
  8. Steroids : 5 outcomes 2 studies in 50 results : IBA
  9. Caspase 3 (Caspase-3) : 5 outcomes in 21 results : IBA
  10. Glycerol (Glycerine) : 4 outcomes 9 studies in 62 results : FDA 6 Generic
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Diseases Related to Brain Edema

  1. Stroke (Strokes)
  2. Ischemia
  3. Brain Ischemia (Cerebral Ischemia)
  4. Brain Injuries (Brain Injury)
  5. Edema
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Key Therapies for Brain Edema

Efficacy Chart >>
  1. Decompressive Craniectomy : 4 outcomes 11 studies in 89 results
  2. Ligation : 3 outcomes 5 studies in 26 results
  3. Craniotomy : 3 outcomes 4 studies in 45 results
  4. Intravenous Infusions : 3 outcomes 3 studies in 13 results
  5. Transplantation (Transplant Recipients) : 3 outcomes 1 study in 18 results
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