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beta-N-Acetylhexosaminidases Summary

Description: A hexosaminidase specific for non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES. Two specific mammalian isoenzymes of beta-N-acetylhexoaminidase are referred to as HEXOSAMINIDASE A and HEXOSAMINIDASE B. Deficiency of the type A isoenzyme causes TAY-SACHS DISEASE, while deficiency of both A and B isozymes causes SANDHOFF DISEASE. The enzyme has also been used as a tumor marker to distinguish between malignant and benign disease.

Also Known As: N-Acetyl-beta-D-hexosaminidase; beta-Hexosaminidase; beta-N-Acetyl-D-hexosaminidase; beta-N-Acetyl-hexosaminidase; N Acetyl beta D hexosaminidase Show All >>

Networked: 414 relevant articles (2 outcomes, 25 trials/studies) for this Bio-Agent

Key Diseases for which beta-N-Acetylhexosaminidases is Relevant

  1. Tay-Sachs Disease : 1 outcome 1 study in 95 results
  2. Neoplasm Metastasis (Metastasis) : 1 outcome 1 study in 3 results
  3. Hepatitis : 1 outcome in 3 results
  4. Alcoholic Liver Diseases (Alcoholic Liver Disease) : 1 outcome in 2 results
  5. Neoplasms (Cancer) : 5 studies in 17 results
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Drugs Related to beta-N-Acetylhexosaminidases

  1. Alkaline Phosphatase
  2. Carcinoembryonic Antigen
  3. Bilirubin
  4. Aspartate Aminotransferases (Aspartate Transaminase)
  5. Isoenzymes
  6. alpha-Mannosidase (LAMAN)
  7. Hexosaminidase A (Hex A)
  8. Glucuronidase
  9. Antigens
  10. Serotonin (5 Hydroxytryptamine)
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Therapies Related to beta-N-Acetylhexosaminidases

  1. Caloric Restriction
  2. Enzyme Therapy
  3. Transplants (Transplant)
  4. Laparoscopic Cholecystectomy
  5. Bone Marrow Transplantation (Transplantation, Bone Marrow)
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