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Basal Cell Nevus Syndrome (Gorlin Syndrome) Summary

Description: Hereditary disorder consisting of multiple basal cell carcinomas, odontogenic keratocysts, and multiple skeletal defects, e.g., frontal and temporoparietal bossing, bifurcated and splayed ribs, kyphoscoliosis, fusion of vertebrae, and cervicothoracic spina bifida. Genetic transmission is autosomal dominant.

Also Known As: Gorlin Syndrome; Nevoid Basal Cell Carcinoma Syndrome; Syndrome, Gorlin; Nevus Syndrome, Basal Cell

Networked: 233 relevant articles (6 outcomes, 21 trials/studies) for this Disease

Key Drugs and Agents for Basal Cell Nevus Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Retinoids : 2 outcomes 1 study in 5 results : IBA
  2. 1-phenyl-3,3-dimethyltriazene (PDT) : 1 outcome 2 studies in 6 results : IBA
  3. Isotretinoin (Accutane) : 1 outcome 1 study in 8 results : FDA 6 Generic
  4. imiquimod (Aldara) : 1 outcome 1 study in 6 results : FDA 4 Generic
  5. Etretinate : 1 outcome 1 study in 5 results : FDA 1
  6. Acitretin : 1 outcome 1 study in 2 results : FDA 1
  7. Peptide Hydrolases (Proteases) : 1 outcome in 1 result : IBA
  8. Gorlin-Goltz Syndrome : 2 studies in 58 results : IBA
  9. DNA (Deoxyribonucleic Acid) : 2 studies in 17 results : IBA
  10. Aminolevulinic Acid (Levulan) : 2 studies in 2 results : FDA 1
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Diseases Related to Basal Cell Nevus Syndrome

  1. Basal Cell Carcinoma (Rodent Ulcer)
  2. Xeroderma Pigmentosum (Kaposi's Disease)
  3. Breast Neoplasms (Breast Cancer)
  4. Odontogenic Cysts (Keratocyst)
  5. Neoplasms (Cancer)
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Key Therapies for Basal Cell Nevus Syndrome

Efficacy Chart >>
  1. Photochemotherapy (Photodynamic Therapy) : 1 outcome 4 studies in 20 results
  2. Bone Marrow Transplantation (Transplantation, Bone Marrow) : 1 outcome 1 study in 1 result
  3. Aftercare (After-Treatment) : 1 study in 3 results
  4. Mohs Surgery (Mohs' Micrographic Surgery) : 1 study in 1 result
  5. Radiotherapy : 5 results
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