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Astrocytoma (Pilocytic Astrocytoma) Summary

Description: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Also Known As: Pilocytic Astrocytoma; Anaplastic Astrocytoma; Juvenile Pilocytic Astrocytoma; Subependymal Giant Cell Astrocytoma; Astrocytoma, Grade I Show All >>

Networked: 5136 relevant articles (165 outcomes, 785 trials/studies) for this Disease

Key Drugs and Agents for Astrocytoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. temozolomide (Temodar) : 16 outcomes 26 studies in 126 results : FDA 3 Generic
  2. Etoposide (VP 16) : 6 outcomes 10 studies in 40 results : FDA 16 Generic
  3. Sirolimus (Rapamycin) : 6 outcomes 6 studies in 27 results : FDA 2
  4. Carboplatin (JM8) : 5 outcomes 9 studies in 31 results : FDA 29 Generic
  5. DNA (Deoxyribonucleic Acid) : 4 outcomes 29 studies in 165 results : IBA
  6. Carmustine (FIVB) : 4 outcomes 18 studies in 78 results : FDA 2
  7. Vincristine (Oncovin) : 3 outcomes 16 studies in 57 results : FDA 17 Generic
  8. Phosphotransferases (Kinase) : 3 outcomes 10 studies in 74 results : IBA
  9. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor) : 3 outcomes 8 studies in 96 results : IBA
  10. Cisplatin (Platino) : 3 outcomes 6 studies in 45 results : FDA 6 Generic
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Diseases Related to Astrocytoma

  1. Glioblastoma (Glioblastoma Multiforme)
  2. Neoplasms (Cancer)
  3. Glioma (Gliomas)
  4. Astrocytoma (Pilocytic Astrocytoma)
  5. Oligodendroglioma
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Key Therapies for Astrocytoma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 25 outcomes 52 studies in 358 results
  2. Radiotherapy : 22 outcomes 64 studies in 386 results
  3. Adjuvant Chemotherapy : 3 outcomes 6 studies in 21 results
  4. Combination Drug Therapy (Combination Chemotherapy) : 2 outcomes 3 studies in 17 results
  5. Ketogenic Diet : 2 outcomes 3 studies in 4 results
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