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Sickle Cell Anemia (Hemoglobin S Disease) Summary

Description: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.

Also Known As: Hemoglobin S Disease; Anemia, Sickle Cell; Sickle Cell Disease; Sickle Cell Disorders; Sickling Disorder Due to Hemoglobin S Show All >>

Networked: 5338 relevant articles (281 outcomes, 608 trials/studies) for this Disease

Key Drugs and Agents for Sickle Cell Anemia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Hydroxyurea (Hydrea) : 62 outcomes 79 studies in 519 results : FDA 6 Generic
  2. Fetal Hemoglobin (Hemoglobin F) : 28 outcomes 29 studies in 360 results : IBA
  3. Hemoglobins (Hemoglobin) : 14 outcomes 39 studies in 528 results : IBA
  4. Penicillins (Penicillin) : 10 outcomes 9 studies in 62 results : FDA 1
  5. Zinc : 9 outcomes 15 studies in 80 results : IBA
  6. Globins : 8 outcomes 18 studies in 188 results : IBA
  7. Iron : 7 outcomes 33 studies in 204 results : IBA
  8. Sickle Hemoglobin : 7 outcomes 17 studies in 281 results : IBA
  9. Oxygen : 5 outcomes 10 studies in 152 results : IBA
  10. deferasirox : 5 outcomes 5 studies in 21 results : FDA 1
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Diseases Related to Sickle Cell Anemia

  1. Thalassemia
  2. beta-Thalassemia (Cooley's Anemia)
  3. Pain (Aches)
  4. Infection
  5. Sickle Cell Anemia (Hemoglobin S Disease)
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Key Therapies for Sickle Cell Anemia

Efficacy Chart >>
  1. Blood Transfusion (Blood Transfusions) : 12 outcomes 33 studies in 198 results
  2. Transplants (Transplant) : 10 outcomes 6 studies in 92 results
  3. Splenectomy : 7 outcomes 9 studies in 91 results
  4. Bone Marrow Transplantation (Transplantation, Bone Marrow) : 6 outcomes 5 studies in 88 results
  5. Transplantation (Transplant Recipients) : 5 outcomes 4 studies in 69 results
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