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Aldehyde Reductase (Aldose Reductase) Summary

Description: An enzyme that catalyzes reversibly the oxidation of an aldose to an alditol. It possesses broad specificity for many aldoses. EC 1.1.1.21.

Also Known As: Aldose Reductase; Aldose Reductase Ia; Aldose Reductase Ib; Erythrose Reductase; Xylose Reductase Show All >>

Networked: 1164 relevant articles (73 outcomes, 167 trials/studies) for this Bio-Agent

Key Diseases for which Aldehyde Reductase is Relevant

  1. Diabetic Neuropathies (Diabetic Neuropathy) : 24 outcomes 29 studies in 140 results
  2. Diabetes Complications : 20 outcomes 28 studies in 290 results
  3. Peripheral Nervous System Diseases (PNS Diseases) : 6 outcomes 6 studies in 36 results
  4. Cataract (Cataracts) : 5 outcomes 27 studies in 212 results
  5. Diabetic Retinopathy (Retinopathy, Diabetic) : 5 outcomes 18 studies in 83 results
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Drugs Related to Aldehyde Reductase

  1. sorbinil
  2. polyol
  3. ONO 2235 (epalrestat)
  4. tolrestat
  5. Streptozocin (Streptozotocin)
  6. Glucose (Dextrose)
  7. fidarestat
  8. Sorbitol (Yal)
  9. Inositol (Myoinositol)
  10. Galactose (Galactopyranose)
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Therapies Related to Aldehyde Reductase

  1. Lenses
  2. Injections
  3. Estrogen Replacement Therapy
  4. Isogeneic Transplantation
  5. Heterologous Transplantation (Xenotransplantation)
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