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Alcoholism (Alcohol Abuse) Summary

Description: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)

Also Known As: Alcohol Abuse; Abuse, Alcohol; Chronic Alcoholic Intoxication; Intoxication, Chronic Alcoholic; Alcoholic Intoxication, Chronic

Networked: 8049 relevant articles (296 outcomes, 986 trials/studies) for this Disease

Key Drugs and Agents for Alcoholism

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Naltrexone (ReVia) : 38 outcomes 45 studies in 202 results : FDA 7 Generic
  2. Disulfiram (Antabuse) : 24 outcomes 34 studies in 380 results : FDA 9
  3. Ethanol (Ethyl Alcohol) : 23 outcomes 106 studies in 899 results : IBA
  4. Acetaldehyde : 13 outcomes 20 studies in 145 results : IBA
  5. acamprosate (AOTA) : 11 outcomes 14 studies in 88 results : FDA 1
  6. Biological Markers (Surrogate Marker) : 9 outcomes 41 studies in 279 results : IBA
  7. Carbon Monoxide : 9 outcomes 39 studies in 279 results : IBA
  8. Lithium : 7 outcomes 11 studies in 35 results : IBA
  9. Serotonin (5 Hydroxytryptamine) : 6 outcomes 27 studies in 159 results : IBA
  10. Aldehyde Dehydrogenase : 6 outcomes 13 studies in 109 results : IBA
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Diseases Related to Alcoholism

  1. Alcoholism (Alcohol Abuse)
  2. Substance-Related Disorders (Drug Abuse)
  3. Neoplasms (Cancer)
  4. Bipolar Disorder (Mania)
  5. Infection
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Key Therapies for Alcoholism

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 14 outcomes 33 studies in 262 results
  2. Self Administration (Administration, Self) : 3 outcomes 3 studies in 24 results
  3. Liver Transplantation : 2 outcomes 1 study in 64 results
  4. Splenectomy : 2 outcomes 1 study in 26 results
  5. Contraception (Birth Control) : 2 outcomes 1 study in 12 results
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