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transglutaminase 2 Summary

Description: TRANSGLUTAMINASE 2 (TGM2 or TGC) is a ubiquitous soluble protein coded by human gene 20q11.2-q12. Tissue transglutaminase is the autoantigen involved in celiac disease. Distinguish from GAMMA-GLUTAMYLTRANSPEPTIDASE that is involved with glutathione metabolism.

Also Known As: G(h) enzyme; TG2 protein, mouse; TGase II; hhGalpha(h); tissue-type transglutaminase Show All >>

Networked: 258 relevant articles (4 outcomes, 17 trials/studies) for this Bio-Agent

Key Diseases for which transglutaminase 2 is Relevant

  1. Neoplasms (Cancer) : 1 outcome 4 studies in 43 results
  2. Renal Cell Carcinoma (Grawitz Tumor) : 1 outcome 3 studies in 5 results
  3. Wounds and Injuries (Trauma) : 1 outcome 1 study in 3 results
  4. Inflammation : 1 outcome in 21 results
  5. Huntington Disease (Huntington's Disease) : 1 outcome in 9 results
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Drugs Related to transglutaminase 2

  1. Proteins (Proteins, Gene)
  2. Cyclin B1
  3. Messenger RNA (mRNA)
  4. Antibodies
  5. 70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)
  6. Metallothionein
  7. HLA-DQ8 antigen
  8. Protein Phosphatase 2 (Protein Phosphatase 2A)
  9. Angiopoietin-1
  10. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
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Therapies Related to transglutaminase 2

  1. Drug Therapy (Chemotherapy)
  2. Chemoprevention
  3. Heterologous Transplantation (Xenotransplantation)
  4. Therapeutics
  5. Injections

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