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ATP dependent 26S protease (26S proteasome) Summary

Description: degrades proteins conjugated to ubiquitin; composed of CF-1,CF-2, & CF-3; CF-2 (also known as 240-kDa proteasome inhibitor) is identical to aminolevulinic acid dehydratase

Also Known As: 26S proteasome; 26 S proteasome complex; 26S protease

Networked: 242 relevant articles (6 outcomes, 21 trials/studies) for this Bio-Agent

Key Diseases for which ATP dependent 26S protease is Relevant

  1. Multiple Myeloma : 4 outcomes 2 studies in 23 results
  2. Neoplasms (Cancer) : 1 outcome 3 studies in 62 results
  3. Osteoarthritis : 1 outcome in 1 result
  4. Chronic Disease (Chronic Diseases) : 1 outcome in 1 result
  5. Prostatic Neoplasms (Prostate Cancer) : 2 studies in 9 results
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Drugs Related to ATP dependent 26S protease

  1. bortezomib (Velcade)
  2. Chymotrypsin
  3. Antioxidants
  4. Proteasome Endopeptidase Complex (Proteasome)
  5. Ubiquitin
  6. benzyloxycarbonylleucyl-leucyl-leucine aldehyde
  7. Sodium
  8. Butyrates (Butyrate)
  9. Heat-Shock Proteins (Heat-Shock Protein)
  10. Type I DNA Topoisomerases (Topoisomerase I)
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Therapies Related to ATP dependent 26S protease

  1. Drug Therapy (Chemotherapy)
  2. Heterologous Transplantation (Xenotransplantation)
  3. Radiotherapy
  4. Chemoprevention
  5. Transplantation (Transplant Recipients)
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