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tripterine Summary

Description: isolated from Tripterygium wilfordii; structure given in first source; potent inhibitory activity on both Kir2.1 and ERG1 potassium channels, leading to LONG QT SYNDROME

Also Known As: celastrol; 3-hydroxy-24-nor-2-oxo-1(10),3,5,7-friedelatetraen-29-oic acid

Networked: 202 relevant articles (19 outcomes, 69 trials/studies) for this Bio-Agent

Key Diseases for which tripterine is Relevant

  1. Neoplasms (Cancer) : 4 outcomes 16 studies in 88 results
  2. Insulin Resistance : 2 outcomes 2 studies in 4 results
  3. Shock : 2 outcomes 1 study in 11 results
  4. Obesity : 2 outcomes in 4 results
  5. Colitis : 2 outcomes in 3 results
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Drugs Related to tripterine

  1. Cytokines
  2. triptolide
  3. Protein Isoforms (Isoforms)
  4. Interleukin-10 (Interleukin 10)
  5. Antibodies
  6. Leptin
  7. Quinine (Quinson)
  8. Collagen Type IV (Type IV Collagen)
  9. Tissue Inhibitor of Metalloproteinase-2
  10. Tissue Inhibitor of Metalloproteinase-1
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Therapies Related to tripterine

  1. Heterologous Transplantation (Xenotransplantation)
  2. Chinese Traditional Medicine (Traditional Chinese Medicine)
  3. Therapeutics
  4. Drug Therapy (Chemotherapy)
  5. Radiotherapy
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