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leflunomide (Arava) Summary

Description: inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway; antagonizes growth-factor mediated smooth muscle cell proliferation in vitro; structure given in first source

Also Known As: Arava; SU101; Aventis Behring Brand of Leflunomide; Aventis Brand of Leflunomide; Aventis Pharma Brand of Leflunomide Show All >>

Networked: 844 relevant articles (123 outcomes, 144 trials/studies) for this Drug

Key Diseases for which leflunomide is Relevant

  1. Rheumatoid Arthritis : 49 outcomes 75 studies in 446 results
  2. Autoimmune Diseases (Autoimmune Disease) : 8 outcomes 1 study in 24 results
  3. Viremia : 8 outcomes 1 study in 12 results
  4. Arthritis (Polyarthritis) : 6 outcomes 9 studies in 52 results
  5. Psoriasis (Pustulosis Palmaris et Plantaris) : 6 outcomes 6 studies in 16 results
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Drugs Related to leflunomide

  1. Methotrexate (Mexate)
  2. infliximab (Remicade)
  3. leflunomide (Arava)
  4. pyrimidine
  5. Intravenous Immunoglobulins (IVIG)
  6. Sulfasalazine (Azulfidine)
  7. Prednisone (Sone)
  8. Tacrolimus (Prograf)
  9. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
  10. Cholestyramine Resin (Questran)
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Therapies Related to leflunomide

  1. Transplants (Transplant)
  2. Heterologous Transplantation (Xenotransplantation)
  3. Drug Therapy (Chemotherapy)
  4. Homologous Transplantation (Allograft)
  5. Organ Transplantation
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