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geldanamycin Summary

Description: unlike the related ansamycins, geldanamycin possesses a methoxyl at C17 on the quinone; from culture filtrates of Streptomyces hygroscopicus var. geldanus var. Nova.

Also Known As: geldanomycin

Networked: 360 relevant articles (10 outcomes, 39 trials/studies) for this Bio-Agent

Key Diseases for which geldanamycin is Relevant

  1. Neoplasms (Cancer) : 3 outcomes 15 studies in 142 results
  2. Carcinoma (Carcinomatosis) : 1 outcome 2 studies in 20 results
  3. Hepatocellular Carcinoma (Hepatoma) : 1 outcome 2 studies in 7 results
  4. Neurodegenerative Diseases (Neurodegenerative Disease) : 1 outcome in 4 results
  5. Ovarian Neoplasms (Ovarian Cancer) : 1 outcome in 4 results
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Drugs Related to geldanamycin

  1. 17-(allylamino)-17-demethoxygeldanamycin (17AAG)
  2. Rifabutin (Ansamycin)
  3. Heat-Shock Proteins (Heat-Shock Protein)
  4. benzoquinone (quinone)
  5. monorden (radicicol)
  6. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
  7. Interleukin-1beta (Interleukin 1 beta)
  8. Synucleins
  9. Interleukin-6 (Interleukin 6)
  10. Ophthalmic Solutions (Eye Drops)
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Therapies Related to geldanamycin

  1. Radiotherapy
  2. Heterologous Transplantation (Xenotransplantation)
  3. Therapeutics
  4. Drug Therapy (Chemotherapy)
  5. Bioreactors
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